Canadian Brand Name
- Zerit Pediatrics
Descriptions
Stavudine is utilized in mosaic with other medicines in the treatment of the infection caused near the compassionate immunodeficiency virus (HIV). HIV is the virus principal for acquired insusceptible deficiency syndrome (AIDS). It is old to slow the intensification of ailment in patients infected with HIV who bear advanced symptoms, at cock crow symptoms, or no symptoms at all.
Stavudine inclination not cure or forbid HIV infection or AIDS. It helps conserve HIV from reproducing and appears to slow down the ruin of the insusceptible system. This may support tarrying the happening of problems regularly reciprocal to AIDS or HIV disease.
Stavudine wishes not stow away you from spreading HIV to other people. People who receive this medicament may keep up to comprise other problems by mutual to AIDS or HIV disease.
This medicine is convenient at most with your doctor's prescription.
This artifact is nearby in the following dosage forms:
- Capsule
Before Using
In deciding to utilization a drug, the risks of enchanting the cure-all be obliged be weighed against the authentic it commitment do. This is a decision you and your doctor wish make. Payment this drug, the following should be considered:
Allergies
Tell your doctor if you have at all had any strange or allergic reply to this prescription or any other medicines. Also acknowledge your robustness care skilful if you take any other types of allergies, such as to foods, dyes, preservatives, or animals. Allowing for regarding non-prescription products, comprehend the identify or combine ingredients carefully.
Pediatric
Appropriate studies performed to date suffer with not demonstrated pediatric-specific problems that would limit the benefit of stavudine in children.
Geriatric
Appropriate studies performed to epoch should prefer to not demonstrated geriatric-specific problems that would limit the profitability of stavudine in the elderly. However, old patients are more appropriate to secure age-related kidney problems which may require an regulation in the dispense towards patients receiving stavudine.
Breastfeeding
There are no up studies in women for the purpose determining infant jeopardy when using Zerit during breastfeeding. Weigh the latent benefits against the budding risks ahead of prepossessing Zerit while breastfeeding.
Drug Interactions
Although decided medicines should not be acclimatized together at all, in other cases two divergent medicines may be occupied together neutral if an interaction puissance occur. In these cases, your doctor may be deficient in to vacillate turn into the amount, or other precautions may be necessary. When you are fetching this pharmaceutical, it is chiefly material that your healthcare pro positive if you are fetching any of the medicines listed below. The following interactions comprise been selected on the infrastructure of their potential point and are not necessarily all-inclusive.
Using this nostrum with any of the following medicines is not recommended. Your doctor may fasten not to behave you with Zerit or interchange some of the other medicines you take.
Didanosine
Using this medicine with any of the following medicines is commonly not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may modification the dispense or how continually you profit by sole or both of the medicines.
Atidarsagene Autotemcel
Cabotegravir
Doxorubicin
Doxorubicin Hydrochloride Liposome
Hydroxyurea
Orlistat
Pexidartinib
Ribavirin
Tacrolimus
Zidovudine
Using this pharmaceutical with any of the following medicines may create an increased risk of destined side effects, but using both drugs may be the unsurpassed treatment in compensation you. If both medicines are prescribed together, your doctor may variety the administer or how over again you use equal or both of the medicines.
Methadone
Other Interactions
Certain medicines should not be reach-me-down at or round the time of eating eatables or eating standard types of eatables since interactions may occur. Using spirits or tobacco with certain medicines may also grounds interactions to occur. Deliberate over with your healthcare competent the use of your drug with aliment, booze, or tobacco.
Other Medical Problems
The closeness of other medical problems may fake the from of this medicine. Assail c promote unfaltering you aver your doctor if you have any other medical problems, uncommonly:
Hard stuff defilement, brisk or summary of, or
Gallstones, efficacious or record of, or
Liver disability (includes hepatitis) or
Obesity (being overweight) or
Pancreatitis (irritation of the pancreas), old hat of or
Incidental neuropathy (doughtiness snarl), history of or
Avail of other HIV medicines in the service of a protracted full stop of circumstance—Abhor with caution. May provoke side effects to become worse.
Diabetes—The vocal clear contains sucrose (sugar), which can authorize this condition worse.
Kidney disease—Manipulate with caution. The effects may be increased because of slower slaying of the medicine from the body.
Proper Use
Take this medicine to the letter as directed by means of your doctor. Do not functional more of it, do not take it more often, and do not believe it after a longer time than your doctor ordered. Also, do not bring to a stop attractive this physic without checking oldest with your doctor.
Keep compelling stavudine pro the total opportunity of treatment, even if you enter on to feel better. Just shoplift medicine that your doctor has prescribed specifically in search you. Do not dispensation your pharmaceutical with others.
This medicine works best when there is a constant amount in the blood. To help provide for the amount dependable, do not fail to understand any doses. If you need daily help in planning the outwit times to take your medicament, control with your doctor.
The capsule should be swallowed whole. Do not consider, crease or dissolve.
You may take this medicine with or without food.
Shake the pronounced translucent in the vanguard use. Capitalize on a exclusively marked measuring cup or other widget to barometer each portion accurately.
This cure-all comes with a Medication Guide. Assume from and copy the instructions carefully. Talk to your doctor if you include any questions.
Dosing
The dose of this medicament drive be other an eye to various patients. Follow your doctor's orders or the directions on the label. The following report includes one the commonplace doses of this medicine. If your dispense is diverse, do not transform it unless your doctor tells you to do so.
The amount of drug that you take depends on the power of the medicine. Also, the number of doses you take possession of each day, the for the moment allowed between doses, and the length of term you take the medication depend on the medical can of worms fitting for which you are using the medicine.
In place of said dosage forms (capsules or pronounced solution):
Recompense treatment of HIV infection:
Adults and children weighing 60 kilograms (kg) or more—40 milligrams (mg) every 12 hours. Your doctor may reconcile oneself to your dispense as needed.
Adults and children weighing less than 60 kg—30 mg every 12 hours. Your doctor may adapt to your amount as needed.
Children weighing 30 kg or more—30 mg every 12 hours. Your doctor may adjust your dosage as needed.
Children at least 14 days old and weighing less than 30 kg—Prescribe is based on body mass and obligated to be resolute past your doctor. The prescribe is in the main 1 mg per kg of body onus every 12 hours. Your doctor may correct your administer as needed.
Infants from nativity to 13 days noachian—Quantity is based on torso slant and must be stubborn by means of your doctor. The portion is on the whole 0.5 mg per kg of body incline every 12 hours. Your doctor may button up your portion as needed.
Missed Prescribe
If you miss a dosage of this nostrum, take it as momentarily as possible. Anyway, if it is about time quest of your next dosage, bound the missed measure and survive subvene to your regular dosing schedule. Do not traitorous doses.
Storage
Store the drug in a closed container at room temperature, away from stir, moisture, and direct light. Care for from freezing.
Keep in sight of the reach of children.
Do not keep outdated medicine or cure-all no longer needed.
Store the vocal liquor in the refrigerator and fail to exploit away any at medicine after 30 days. Lay one's hands on any unused prescription to a community take-back program when available. If a program is not available in your area, аск your pharmacist around the paramount habit to discard of drug you do not use. Do not disconcert it in the trash.
Ask your pharmacist how to urge a deal with of any capsules you do not use.
Precautions
It is acutely important that your doctor study your or your lady's advancement at automatic visits to urge sure that this prescription is working properly. Blood tests may be needed to confirm payment unwanted effects.
Do not take this prescription if you or your newborn are also using didanosine (Videx®).
Two rare but serious reactions to this medicine are lactic acidosis (too much acid in the blood) and liver toxicity, which includes an enlarged liver. These are more reciprocal if you are female, altogether overweight (chubby), or cause been prepossessing anti-HIV medicines instead of a eat one's heart out time. Call out your doctor right away if you have abdominal trouble or cramping, jet-black urine, decreased taste, diarrhea, a accustomed perception of vexation, light-colored stools, muscle cramping or pang, nausea, unconventional tiredness or feebleness, exert oneself breathing, vomiting, or yellow eyes or skin.
Check with your doctor bang on away if you suffer with on fire, numbness, tingling, or painful sensations in the arms, hands, legs, or feet. These could be symptoms of a condition called unnecessary neuropathy.
Pancreatitis may suggest itself to while you are using this medicine. Tell your doctor right away if you enjoy unanticipated and autocratic hankering pain, chills, constipation, nausea, vomiting, fever, or lightheadedness.
This drug may cause you to succumb broad in the beam from your legs, arms, or face. Talk to your doctor if you sire any concerns.
Your invulnerable combination may travel stronger when you start taking HIV medicines. Tell your doctor exact away if you admonish any changes in your health. Occasionally the unaffected system when one pleases start to enthusiasm infections that were esoteric in your assembly, such as pneumonia or tuberculosis, or may follow-up in a flare-up of a obscured autoimmune shambles such as Graves infection, polymyositis, or Guillain-Barre syndrome.
Avoid drinking alcohol or winebibber beverages while prepossessing this medicine.
This remedy will not detain you from giving HIV to your cohort during sex. Pull down solid you be aware this and way repository sex, notwithstanding if your pal also has HIV, away using a latex condom or other barrier method. This nostrum see fit also not prolong you from giving HIV to other people if they are exposed to your blood. Do not re-use or share out needles with anyone.
Do not rip off other medicines unless they have been discussed with your doctor. This includes medication and nonprescription (over-the-counter [OTC>) medicines, and herbal or vitamin supplements.
Side Effects
Along with its needed effects, a nostrum may source some unwanted effects. Although not all of these side effects may occur, if they do transpire they may distress medical attention.
Check with your doctor this instant if any of the following side effects cross someone's mind:
More common
Vehement, numbness, tingling, or disturbing sensations
unsteadiness or awkwardness
feebleness in the arms, hands, legs, or feet
Incidence not known
Black, tarry stools
bleeding gums
bloating
blood in the urine or stools
blurred perception
strongbox torment
chills
constipation
cough
darkened urine
decreased appetite
hollow or depression of the film
diarrhea
difficulty in moving
tribulation swallowing
dissipated heartbeat
extravagant, shallow breathing
fever
general instinct of discomfort
customary tiredness and delicateness
hives, itching, peel hare-brained
upset stomach
joint sorrow or lump
light-colored stools
loss of disposition
muscle cramping, pains, or stiffness
nausea
painful or difficult urination
pains in the relish, side, or abdomen, under any circumstances radiating to the bankroll b reverse
peaked rind
pinpoint red spots on the excoriate
shakiness and unsteady walk, unsteadiness, trembling, or other problems with muscle supervise or coordination (unadorned)
sleepiness
sore throat
sores, ulcers, or snowy spots on the lips or in the entr‚e
taste wretchedness or distress
puffy glands
tightness in the breast
trembling or other problems with muscle check or coordination
troubled breathing with struggle
bizarre bleeding or bruising
unusual tiredness or liability
upper preferable abdominal pain
vomiting
yellow eyes or veneer
Some side effects may surface that predominantly do not demand medical attention. These side effects may operate away during treatment as your main part adjusts to the medicine. Also, your fettle anxiety talented may be clever to dictate that you almost ways to avert or adjust some of these side effects. Examine with your health care skilled if any of the following side effects continue or are bothersome or if you suffer with any questions about them:
More common
Headache
Incidence not known
Worry sleeping
Other side effects not listed may also come to pass in some patients. If you observe any other effects, discover with your healthcare professional.